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IL 4 signaling pathway
来自 : 发布时间:2024-11-29

Interleukin4(IL-4)isacytokinethatcanleadtodevelopmentofTh2cells.The140kDIL-4Receptor(CD124)isfoundonmanycelltypes,eventhoseofnon-hematopoieticOrigen.Thereceptorisformedfromtwochains:IL-4R(alpha)andtheIL-2Rgammachain(CD132).PrimarysignalingisthroughtheJAK/Stat6pathwayandMAPKs.

Contributor:

REFERENCES:HintonHJ,WelhamMJ.1999.Cytokine-inducedproteinkinaseBactivationandBadphosphorylationdonotcorrelatewithcellsurvivalofhemopoieticcells.JImmunol15;162(12):7002-9.

本文链接: http://ig.immuno-online.com/view-1545760957.html

发布于 : 2024-11-29 阅读()